Postdoctoral Position: Spatiotemporal Mechanisms Controlling Circadian Rhythms and
Sleep, Yadlapalli Lab, University of Michigan
The Yadlapalli Lab in the Department of Cell and Developmental Biology has pioneered cell
biological approaches that visualize individual clock mRNAs, genes, and proteins with
subcellular resolution in intact Drosophila brains. We use this capability, together with fly
neurogenetics, proteomics, RNA biology, multi-omics, and quantitative imaging, to ask how the
spatiotemporal organization of clock components in clock neurons controls circadian rhythms.
We are recruiting a postdoctoral fellow to lead independent projects in one of the following
research areas:
* Clock protein condensates and their role in circadian rhythm regulation
* Clock mRNA splicing and localization – how is it affected by temperature and the
underlying regulatory mechanisms
* Chromatin accessibility at clock-controlled genes
* Sleep regulation – molecular and cellular mechanisms
Projects are designed to advance ongoing research while building toward each fellow’s future
independent program.
Funding & environment. The lab is supported by NIH R35 (MIRA) and NIH R01 awards,
providing stable, long-horizon funding for ambitious projects. Fellows receive direct mentorship
on grant writing, publication strategy, and the academic job market, and join an active
circadian/sleep community at Michigan. International postdocs will be sponsored a H1-visa and
the stipend levels are set at NIH levels.
Qualifications:
* Ph.D. in neurobiology, molecular biology, cell biology, genetics, biochemistry, or a
related field
* Strong interest in circadian biology, sleep, or adjacent areas
* Experience with Drosophila genetics, imaging, RNA biology, biochemistry, or omics is a
plus but not required

To apply. Send a single PDF to swathi@umich.edu containing: (1) a cover letter describing
research experience, career goals, and fit; (2) CV with publication list and a one-paragraph
contribution summary for each paper; (3) names and contact information for three references.
Learn more
Lab: https://yadlapallilab.org
Publications: https://scholar.google.com/citations?user=otQ6T6gAAAAJ&hl=en
Inquiries to Dr. Swathi Yadlapalli, swathi@umich.edu